ZW Zhe Wang PLANT PATHOLOGY · MICROBIOME植物病理 · 微生物组
Phyllosphere ecology · Plant health叶际生态 · 植物健康

Where plants,pathogens& microbesmeet 在植物、病原微生物相遇之处

I am a Ph.D. student in the Kenichi Tsuda lab at Huazhong Agricultural University. I combine multi-omics, microbial ecology, and mechanistic experiments to understand how microbial communities influence plant health and disease outcomes. 我是华中农业大学津田贤一实验室的博士研究生。我结合多组学、微生物生态学与机制实验,研究微生物群落如何影响植物健康与病害结局。

A living interface under pressure压力之下的生命界面

My work asks how plants recruit, shape, or depend on microbial communities when pathogens enter the system—and how those relationships alter disease outcomes.我的研究关注:当病原进入系统后,植物如何招募、塑造或依赖微生物群落,以及这些关系如何改变病害结局。

I am particularly interested in how microbial members in the phyllosphere influence host health, pathogen behavior, and microbiome-mediated disease outcomes.我尤其关注叶际微生物成员如何影响宿主健康、病原行为,以及由微生物组介导的病害结果。

Methodologically, I connect data-rich approaches with mechanistic questions. That means combining multi-omics and microbial ecology with carefully designed experiments rather than treating any single technique as sufficient on its own.在方法上,我把数据密集型手段与机制问题连接起来,将多组学和微生物生态学与精心设计的实验结合,而不把任何单一技术视为全部答案。

Core questions核心问题

  • Phyllosphere microbiome assembly and function叶际微生物组的组装与功能
  • Microbiome-mediated disease suppression微生物组介导的病害抑制
  • Host control of microbial community dynamics宿主对微生物群落动态的调控

Current system当前体系

  • Maize–Bipolaris maydis–microbiome interactions玉米–Bipolaris maydis–微生物组互作
  • Phyllosphere ecology under pathogen pressure病原压力下的叶际生态学

Publications & scientific commentary论文与科学评论

A focused selection of recent work, including my original reflection on the path behind each publication. The complete record is available on the Scientific CV page.以下为近期代表性成果,并保留我对每篇文章发表过程的原始感悟;完整发表记录见学术简历页面。

Graphical abstract for the 2026 Plant and Cell Physiology commentary
2026 · Commentary · Sole author2026 · 述评 · 唯一作者

Living with the enemy: plants outsource their defense to fungal gatekeepers

Wang Z*. Plant and Cell Physiology, pcag004.

Host-mediated endophyte–pathogen competition and asymptomatic fungal colonization.聚焦宿主介导的内生真菌–病原竞争与无症状真菌定殖。

My original context & reflection我的原始背景与感悟

This article comments on Kei Hiruma, Kuldanai Pathompitaknukul, Hiroyuki Tanaka, Yuki Iwaguchi, Shunsuke Miyashima, Nanami Kawamura, Atsushi Toyoda, Takehiko Itoh, and Yusuke Saijo, “Host-mediated endophyte-pathogen competition in roots enables asymptomatic fungal colonization in Arabidopsis thaliana,” Plant and Cell Physiology, 2025, pcaf126.这篇文章是对 Kei Hiruma、Kuldanai Pathompitaknukul、Hiroyuki Tanaka、Yuki Iwaguchi、Shunsuke Miyashima、Nanami Kawamura、Atsushi Toyoda、Takehiko Itoh 和 Yusuke Saijo 论文的 Commentary,主题是根部内生真菌与病原在宿主介导下的竞争如何帮助 Arabidopsis thaliana 实现无症状真菌定殖。

The manuscript went through repeated revisions and a winding path before publication. With Ken's support, it was eventually published under my sole authorship, which made it especially meaningful to me.这篇稿件经历了反复修改与颇为曲折的发表过程,最终在 Ken 的支持下以我唯一作者的身份发表,因此对我而言格外重要。

Chinese version ↗中文解读 ↗
Graphical abstract for the 2025 Crop Health commentary
2025 · Commentary2025 · 述评

Harnessing Aspergillus and host M genes for sustainable phyllosphere microbiome engineering

Wang Z, Yin JK, Tsuda K*. Crop Health, 3(1):6.

A perspective on sustainable phyllosphere microbiome engineering.关于可持续叶际微生物组工程的科学评论。

My original reflection我的原始感悟

Originally developed from a Ph.D. course assignment, then refined into a Spotlight-style commentary and eventually published in Crop Health.这篇工作最初来源于博士课程作业,随后被打磨成 Spotlight 风格的评论文章,最终发表在 Crop Health

Chinese version ↗中文解读 ↗
Graphical abstract for the 2024 Annual Review of Phytopathology paper
2024 · Review · Co-first author2024 · 综述 · 共同第一作者

Regulation of bacterial growth and behavior by host plant

Nakagami S#, Wang Z#, Han XW, Tsuda K*. Annual Review of Phytopathology, 62:12.1–12.28.

How host plants regulate bacterial growth and behavior.宿主植物如何调控细菌生长与行为。

My original reflection我的原始感悟

My first paper published as a co-first author, centered on how host plants regulate bacterial growth and behavior.这是我第一次以共同第一作者身份发表的论文,聚焦宿主植物如何调控细菌生长与行为。

Chinese version ↗中文解读 ↗

From community data to mechanism从群落数据到作用机制

An experimental and computational toolkit built around the biological question.围绕生物学问题组织实验与计算工具,而非让技术替代问题本身。

M01

Methods & data方法与数据

Amplicon sequencing, metagenomics, RNA-seq, scRNA-seq, multi-omics interpretation, and reproducible analysis.扩增子测序、宏基因组、RNA-seq、scRNA-seq、多组学解读与可复现分析。

M02

Experimental systems实验体系

Microbe isolation and culture, molecular cloning, vector construction, yeast transformation, qPCR, and microscopy.微生物分离培养、分子克隆、载体构建、酵母转化、qPCR 与显微观察。

M03

Computational tools计算工具

R, Shell, server management, data visualization, figure preparation, and AI-assisted research workflows.R、Shell、服务器管理、数据可视化、科研作图与 AI 辅助科研工作流。

M04

Communication科研传播

Scientific writing, visual abstract design, oral presentation, and public-facing research commentary.学术写作、图形摘要设计、口头汇报与面向公众的科研评论。

Research made discussable让研究可以被讨论

Alongside papers and conference work, I write public-facing research notes, commentary, and reflections in Chinese.除了论文与会议工作,我也持续用中文撰写面向公众的科研笔记、学术评论与个人思考。

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